Human Metabolome Technologies (HMT) in Japan has developed a novel method for metabolome analysis using CE-MS (Capillary Electrophoresis-Mass Spectrometry). CE-MS is a perfect method for comprehensive metabolite analysis. HMT has the world’s best CE-MS lab and technology. Orders require no minimum number of samples
CE-MS analysis can be applied in various areas including toxicity prediction, drug mechanism of action, bio-processing and disease marker discovery. Diverse samples such as blood, urine, CSF, organs, cultured cells, microbes, and plants can be analyzed. Analysis of glycolysis cycle metabolites is also one of HMT’s great strengths.
No other analytical platform can detect ionic compounds like phosphorylated organic acids and nucleotides as well as CE-MS.
CE-MS is a combination of capillary electrophoresis (CE) and mass spectrometry (MS). CE-MS enables an incredible measurement capability with high-speed separation, high resolution, and high sensitivity for ionic compounds. Furthermore, combination of CE-MS with liquid chromatography mass spectrometry (LC-MS) permits the identification of all metabolites in a cell, including both ionic and neutral compounds.
Separated by Ion charge
and Ion radius
HMT’s CE-MS features:
Fast analysis High sensitivity measurement High separation capability
Example of Detectable Metabolites
+ Cation Mode
- Anion Mode
Amino Acids
Gly
B-Ala
GABA
Ser
Pro
Val
Homoserine
Thr
Cys
Hydroxyproline
Ile
Leu
Asn
Ornithine
Asp
Gln
Lys
Glu
Met
His
Phe
Arg
Citruline
Tyr
Trp
Orders require no minimum number of samples
HMT's metabolite library includes about 900 compounds.